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      N-Ethyl-2-pyrrolidone (NEP)

      • Product Name: N-Ethyl-2-pyrrolidone (NEP)
      • CAS: 2687-91-4
      • Purity:
      • Appearance: clear liquid

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      Inquiry

      Factory supply N-Ethyl-2-pyrrolidone (NEP) 2687-91-4 with sufficient stock and high standard

      • Molecular Formula:C6H11NO
      • Molecular Weight:113.159
      • Appearance/Colour:clear liquid 
      • Vapor Pressure:0.276mmHg at 25°C 
      • Melting Point:87.5-88.5 °C 
      • Refractive Index:n20/D 1.465(lit.)  
      • Boiling Point:203.6 °C at 760 mmHg 
      • PKA:-0.41±0.20(Predicted) 
      • Flash Point:76.1 °C 
      • PSA:20.31000 
      • Density:0.993 g/cm3 
      • LogP:0.56660 

      N-Ethyl-2-pyrrolidone(Cas 2687-91-4) Usage

      Flammability and Explosibility

      Nonflammable

      Safety Profile

      Moderately toxic by ingestion. An eye irritant. Combustible. When heated to decomposition it emits toxic fumes of NOx.

      General Description

      1-Ethyl-2-pyrrolidone is a transdermal absorption-enhancing compound and mechanism of its effect on multilammellar liposome of stratum corneum lipid has been studied.

      InChI:InChI=1/C6H11NO/c1-2-7-5-3-4-6(7)8/h2-5H2,1H3

      2687-91-4 Relevant articles

      -

      Leonard,Simon

      , p. 1262,1265 (1952)

      -

      -

      Rando,R.R.

      , p. 1629 - 1631 (1972)

      -

      -

      Sakurai

      , p. 41 (1936)

      -

      Ultra-fast Cycling for Multiplexed Cellular Fluorescence Imaging

      Ahmed, Maaz S.,Carlson, Jonathan C. T.,Ko, Jina,Oh, Juhyun,Weissleder, Ralph

      , (2020)

      Rapid analysis of single and scant cell ...

      Chemoselective Hydrogenation of Olefins Using a Nanostructured Nickel Catalyst

      Klarner, Mara,Bieger, Sandra,Drechsler, Markus,Kempe, Rhett

      supporting information, p. 2157 - 2161 (2021/05/21)

      The selective hydrogenation of functiona...

      Photoredox-Catalyzed Simultaneous Olefin Hydrogenation and Alcohol Oxidation over Crystalline Porous Polymeric Carbon Nitride

      Qiu, Chuntian,Sun, Yangyang,Xu, Yangsen,Zhang, Bing,Zhang, Xu,Yu, Lei,Su, Chenliang

      , p. 3344 - 3350 (2021/07/26)

      Booming of photocatalytic water splittin...

      N-Alkylation of N-trimethylsilyl derivatives of lactams, amides, and imides with alkyl sulfonates

      Baukov, Yu. I.,Kramarova, E. P.,Negrebetsky, Vad. V.,Shagina, A. D.,Shipov, A. G.,Tarasenko, D. V.

      , p. 398 - 400 (2020/04/15)

      The reaction of N-trimethylsilyl derivat...

      Bidentate NHC-Cobalt Catalysts for the Hydrogenation of Hindered Alkenes

      Wei, Zeyuan,Wang, Yujie,Li, Yibiao,Ferraccioli, Raffaella,Liu, Qiang

      , p. 3082 - 3087 (2020/10/02)

      Herein, we report a series of easily acc...

      2687-91-4 Process route

      N-trimethylsilyl-pyrrolidin-2-one
      14468-90-7

      N-trimethylsilyl-pyrrolidin-2-one

      Ethyl benzenesulfonate
      515-46-8

      Ethyl benzenesulfonate

      1-ethyl-2-pyrrolidinone
      2687-91-4

      1-ethyl-2-pyrrolidinone

      trimethylsilyl benzenesulfonate
      17882-06-3

      trimethylsilyl benzenesulfonate

      Conditions
      Conditions Yield
      Heating;
      59%
      72%
      1-(2-hydroxyethyl)-2-pyrrolidinone
      3445-11-2

      1-(2-hydroxyethyl)-2-pyrrolidinone

      2-pyrrolidinon
      616-45-5

      2-pyrrolidinon

      1-ethyl-2-pyrrolidinone
      2687-91-4

      1-ethyl-2-pyrrolidinone

      1-ethenyl-2-pyrrolidinone
      88-12-0

      1-ethenyl-2-pyrrolidinone

      Conditions
      Conditions Yield
      0.37 - 1.6 % cesium on silica; In water; at 350 - 375 ℃; for 3 - 95h; Product distribution / selectivity;
       
      0.37 - 1.6 % cesium on silica; at 350 - 375 ℃; for 3 - 95h; Product distribution / selectivity;
       

      2687-91-4 Upstream products

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      2687-91-4 Downstream products

      • 107470-29-1
        107470-29-1

        N-ethyl-3-trifluoroacetyl-2-pyrrolidone

      • 131657-47-1
        131657-47-1

        (E)-N-(1-ethylpyrrolidin-2-ylidene)-4-methylbenzenesulfonamide

      • 2314-78-5
        2314-78-5

        N-ethylsuccinimide

      • 932-17-2
        932-17-2

        N-acetylpyrrolidinone

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